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Chitosan–Collagen-Hydroxyapatite Nanocomposite Biomaterials Deposited on Ti-6Al-4V and ZrO2 Nanotube for Bones Healing

Authors : Asma H. Mohammed , Marwa Abdul Muhsien Hassan
Department of Physics, College of Science, Al-Mustansyriah University

Author :Majid Shannon Khalaf
Department of Chemistry, College of Science, Al-Nahrain University

DOI: http://dx.doi.org/10.24086/cuesj.si.2017.n2a17

Abstract

Chitosan–Collagen -Hydroxyapatite nanocomposite biomaterials deposited on Ti-6Al-4V and ZrO2 nanotube  for bones healing. The hexagonal structure of HAp pattern has been realized. EDX  showed the proportion of Ca:P ranging between 1.57 and 1.87. The smaller particle size with homogeneous size distribution has been shown in SEM picture. The radiographic evaluation appeared that there were no areas of radiolucency between the nano coated implant and adjacent cortical bone in the radiographic examination and also there was increase in thickness of cortical bone around the implants after 6 weeks healing periods.

Keyword: Chitosan–Collagen –Hydroxyapatite, Ti-6Al-4V and ZrO2 Nanotube, Bones Healing.

Refrences

[1] Mobasherpour, I., Heshajin, M. S., Kazemzadeh, A., M. Zakeri, M., 2007, ‘‘Synthesis of Nanocrystalline Hydroxyapatite by using Precipitation Method,’’ J. Alloys Compd., Vol. 430, pp. 330-333.

[2] Parthiban, S.P., Elayaraja, K., Girija, E. K., Yokogawa, Y., Kesavamoorthy, R., Palanichamy, M., Asokan, K., and Narayana Kalkura, S., 2009, “Preparation of thermally stable nanocrystalline hydroxyapatite by hydrothermal method.” J. Mater. Sc: Mater. Med., Vol. 20, pp. 77-83.

[3] Kim, W., Zhang, Q., and F. Saito., 2000, “Mechanochemical synthesis of hydroxyapatite from Ca(OH)2-P2O5 and CaO- Ca(OH)2-P2O5 mixtures.” J. Mater. Sci., Vol. 35, pp. 5401-5405.

[4] Balamurugan, A., Kannan, S., and Rajeswari S., 2002, “Bioactive sol-gel hydroxyapatite surface for biomedical applications-in vitro study.” Trends. Biomater. Artif. Organs, Vol. 16, pp. 18-20.

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