Preventive Effect of Both Vitamin C and E on Sperm Abnormalities Caused by Nicotine in Male Albino Mice

Authors: Galawezh Obaid Othman,Nadhum jalal esmaeil
Department of Biology, college of Education,University of Salahaddin –Erbil

DOI: http://dx.doi.org/10.24086/cuesj.si.2017.n2a14


The aim of our study was to detect  the preventive effect of both vitamin C (Ascorbic acid) and vitamin E  (α- tocopherol) on the sperm abnormalities in laboratory albino mice Mus musculus nicotine was administrated using three concentrations (10,20 ad 30 µg/ mouse) through four doses daily (from 7:00 am to 7:00 pm) and for three different  periods (15,30 and 45 days) while vitamin C & E  were administrated half hour before and after nicotine administration with dose (100 ug/ mouse & 0.6 I.U/mouse) respectively The following results were observed ability of nicotine to increase all types of qualitative sperm abnormalities in male mice significantly (sperm without tail, sperm without head, swollen head sperm, defective head sperm, defective hook sperm,& hook sperm) significantly at (P< 0.01), Testing the effects of vitamin C on nicotine which showed a strong antagonized effect on nicotine while vitamin (E) did not show a significant effect.

Keywords: component; Nicotine effect, sperm abnormalities, and antioxidant.



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